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A Closer Look to Polyesters: Properties, Synthesis, Characterization, and Particle Drug Delivery Applications

[ Vol. 11 , Issue. 5 ]

Author(s):

Katherine Pazmiño Viteri*, Karla Sofía Vizuete, Frank Alexis, Brajesh Kumar and Alexis Debut   Pages 4 - 38 ( 35 )

Abstract:


Background: Natural and synthetic polymeric materials can be used in the fields of biomedicine and pharmaceuticals as a material for controlled drug delivery. Among the synthetic polymers, polyesters are synthesized from two natural monomers: lactic and glycolic acid, which are biocompatible and biodegradable.

Objective: Here, we review broad aspects of polyesters including its properties, synthesis, characterization, and particle drug delivery applications.

Conclusion: Finally, we have concluded that polyesters are certainly very versatile material that are continuously reinvented for future application in new areas of science and medicine. However, several aspects must be considered when synthesizing polyesters, which have a direct influence on biodegradability and biocompatibility. These properties may limit the performance of in vitro and in vivo tests.

Keywords:

Polyesters, polymers, biodegradable, nanoparticles, microparticles, drug delivery.

Affiliation:

Laboratorio de Caracterización de Nanomateriales, CENCINAT, Universidad de las Fuerzas Armadas ESPE, Sangolquí, Laboratorio de Caracterización de Nanomateriales, CENCINAT, Universidad de las Fuerzas Armadas ESPE, Sangolquí, Escuela de Ciencias Biológicas e Ingeniería, Universidad Yachay Tech, Ibarra, ChemNanoBio Research Laboratory, Department of Chemistry, TATA College, Chaibasa, Laboratorio de Caracterización de Nanomateriales, CENCINAT, Universidad de las Fuerzas Armadas ESPE, Sangolquí

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