Submit Manuscript  

Article Details


Nano Technological Approaches for Anti-Tumour Therapy: Opportunities and Challenges

Author(s):

Krishna Champaneria* and Prajesh Prajapati   Pages 1 - 12 ( 12 )

Abstract:


Cancer is one of the reason for mortality and its individual and collective impact is substantial. Conventional chemotherapy utilizes drugs that can destroy Tumor cells effectively. But these agents destroy healthy cells along with the tumor cells, leading to many adverse effects which include hypersensitivity reactions, nephrotoxicity, and neurotoxicity. To minimize the adverse effects, various drug delivery systems (DDSs) has been developed. Among them, nanoparticles are attractive platforms for it. So this review paper explores the recent work done on targeted delivery, enhancing tumor accumulation and longer blood circulation using more effective biomaterial that will enhance the properties of nanoparticles. Moreover, various target-specific delivery of drugs like antibody-targeted, targeting delivery through angiogenesis, mitochondria, CD44 receptor are also explained.

Keywords:

Nanotechnology, Targeted delivery, General principles, Nanoparticles, Tumour

Affiliation:

Institute of Research and Development, Gujarat Forensic Sciences University, Gandhinagar-382007, Gujarat, Institute of Research and Development, Gujarat Forensic Sciences University, Gandhinagar-382007, Gujarat



Read Full-Text article