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Microwave-assisted Efficient One-pot Synthesis of Nitriles Using Recyclable Magnetite (Fe3O4) Nanoparticles as Catalyst and Water as Solvent: A Greener Approach

[ Vol. 10 , Issue. 4 ]

Author(s):

Prashant Chavan*, Suhas Pednekar, Ramesh Chaughule and Anushree Lokur   Pages 507 - 517 ( 11 )

Abstract:


Background: There has been an increasing curiosity over the past few years to carry out organic reactions over heterogeneous nanocatalysts. Microwave activation coupled with a nanocatalyst along with water as a reaction medium makes the process further green. Microwave activation as a green process reduces reaction times, enhances product purity and improves chemical yield.

Methods: Nitrile group chemistry has been explored by many researchers across the globe owing to its interesting properties and its importance in synthetic chemistry. Despite several methods being available for the synthesis of nitriles, microwave assisted synthesis of nitriles using Fe3O4 nanoparticles appears more promising. The present study is intended at developing a recyclable magnetite (Fe3O4) nanoparticles catalyzed protocol towards the synthesis of organonitrile derivatives using one pot reaction.

Results: The above protocol incorporates the use of microwave for heating and water as reaction medium. Several substituted nitriles could be synthesized for excellent yields. The magnetite nanoparticles can be reused for new reaction without significant loss in activity.

Conclusion: The experiment makes the protocol simple, environment friendly and economically feasible.

Keywords:

Fe3O4 nanoparticles, microwave, one-pot synthesis of nitriles, recyclability, water as solvent.

Affiliation:

Department of Chemistry, Ramnarain Ruia Autonomous College, Matunga, Mumbai, National Center for Nanoscience and Nanotechnology, University of Mumbai, Mumbai, Department of Chemistry, Ramnarain Ruia Autonomous College, Matunga, Mumbai, Department of Chemistry, Ramnarain Ruia Autonomous College, Matunga, Mumbai

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